Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas | Zendy

Eva Dombi | Zendy; Andrea Baldwin | Zendy; Leigh Marcus | Zendy; Michael J. Fisher | Zendy; Brian Weiss | Zendy; AeRang Kim | Zendy; Patricia Whitcomb | Zendy; Staci Martin | Zendy; Lindsey AschbacherSmith | Zendy; Tilat A. Rizvi | Zendy; Jianqiang Wu | Zendy; Rachel Ershler | Zendy; Pamela L. Wolters | Zendy; Janet Therrien | Zendy; John Glod | Zendy; Jean B. Belasco | Zendy; Elizabeth K. Schorry | Zendy; Alessandra Brofferio | Zendy; Amy J. Starosta | Zendy; Andrea Gillespie | Zendy; Austin L. Doyle | Zendy; Nancy Ratner | Zendy; Brigitte C. Widemann | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas

Author(s) -

Eva Dombi,

Andrea Baldwin,

Leigh Marcus,

Michael J. Fisher,

Brian Weiss,

AeRang Kim,

Patricia Whitcomb,

Staci Martin,

Lindsey AschbacherSmith,

Tilat A. Rizvi,

Jianqiang Wu,

Rachel Ershler,

Pamela L. Wolters,

Janet Therrien,

John Glod,

Jean B. Belasco,

Elizabeth K. Schorry,

Alessandra Brofferio,

Amy J. Starosta,

Andrea Gillespie,

Austin L. Doyle,

Nancy Ratner,

Brigitte C. Widemann

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1605943

Subject(s) - medicine , selumetinib , neurofibromatosis , plexiform neurofibroma , neurofibromatosis type i , neurofibromin 1 , neurofibromatosis type 2 , dermatology , neurofibroma , pathology , cancer , colorectal cancer , kras

Effective medical therapies are lacking for the treatment of neurofibromatosis type 1-related plexiform neurofibromas, which are characterized by elevated RAS-mitogen-activated protein kinase (MAPK) signaling.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research