Transmission of Extensively Drug-Resistant Tuberculosis in South Africa
Author(s) -
Neha Shah,
Sara C. Auld,
James C. M. Brust,
Barun Mathema,
Nazir Ismail,
Pravi Moodley,
Koleka Mlisana,
Salim Allana,
Angela Campbell,
Thuli Mthiyane,
Natashia Morris,
Primrose Mpangase,
Hermina van der Meulen,
Shaheed Vally Omar,
Tyler S. Brown,
Apurva Narechania,
Elena Shaskina,
Thandi Kapwata,
Barry N. Kreiswirth,
Neel R. Gandhi
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1604544
Subject(s) - tuberculosis , medicine , transmission (telecommunications) , mycobacterium tuberculosis , drug resistance , psychological intervention , extensively drug resistant tuberculosis , interquartile range , cluster (spacecraft) , genotype , virology , public health , environmental health , pathology , psychiatry , biology , microbiology and biotechnology , biochemistry , electrical engineering , computer science , gene , engineering , programming language
Drug-resistant tuberculosis threatens recent gains in the treatment of tuberculosis and human immunodeficiency virus (HIV) infection worldwide. A widespread epidemic of extensively drug-resistant (XDR) tuberculosis is occurring in South Africa, where cases have increased substantially since 2002. The factors driving this rapid increase have not been fully elucidated, but such knowledge is needed to guide public health interventions.
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