Endemic Scrub Typhus in South America | Zendy

Thomas Weitzel | Zendy; Sabine Dittrich | Zendy; Javier López | Zendy; Weerawat Phuklia | Zendy; Constanza Martínez-Valdebenito | Zendy; Katia Velásquez | Zendy; Stuart D. Blacksell | Zendy; Daniel H. Paris | Zendy; Katia Abarca | Zendy

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Endemic Scrub Typhus in South America

Author(s) -

Thomas Weitzel,

Sabine Dittrich,

Javier López,

Weerawat Phuklia,

Constanza Martínez-Valdebenito,

Katia Velásquez,

Stuart D. Blacksell,

Daniel H. Paris,

Katia Abarca

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1603657

Subject(s) - scrub typhus , orientia tsutsugamushi , zoonosis , typhus , rickettsiosis , geography , virology , medicine , rickettsia , virus

Scrub typhus is a life-threatening zoonosis caused by Orientia tsutsugamushi organisms that are transmitted by the larvae of trombiculid mites. Endemic scrub typhus was originally thought to be confined to the so called "tsutsugamushi triangle" within the Asia-Pacific region. In 2006, however, two individual cases were detected in the Middle East and South America, which suggested that the pathogen was present farther afield. Here, we report three autochthonous cases of scrub typhus caused by O. tsutsugamushi acquired on Chiloé Island in southern Chile, which suggests the existence of an endemic focus in South America. (Funded by the Chilean Comisión Nacional de Investigación Científica y Tecnológica and the Wellcome Trust.).

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