70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer | Zendy

Fátima Cardoso | Zendy; Laura J. van’t Veer | Zendy; Jan Bogaerts | Zendy; Leen Slaets | Zendy; Giuseppe Viale | Zendy; Suzette Delaloge | Zendy; JeanYves Pierga | Zendy; Étienne Brain | Zendy; Sylvain Causeret | Zendy; Mauro Delorenzi | Zendy; Annuska M. Glas | Zendy; Vassilis Golfinopoulos | Zendy; Theodora Goulioti | Zendy; Susan Knox | Zendy; Erika Matos | Zendy; Bart Meulemans | Zendy; Peter A. Neijenhuis | Zendy; Ulrike Nitz | Zendy; Rodolfo Passalacqua | Zendy; Peter M. Ravdin | Zendy; Isabel T. Rubio | Zendy; Mahasti Saghatchian | Zendy; Tineke J. Smilde | Zendy; Christos Sotiriou | Zendy; Lisette Stork | Zendy; Carolyn Straehle | Zendy; Geraldine Thomas | Zendy; Alastair M. Thompson | Zendy; Jacobus M. van der Hoeven | Zendy; Peter Vuylsteke | Zendy; René Bernards | Zendy; Konstantinos Tryfonidis | Zendy; Emiel J. Rutgers | Zendy; Martine Piccart | Zendy

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70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

Author(s) -

Fátima Cardoso,

Laura J. van’t Veer,

Jan Bogaerts,

Leen Slaets,

Giuseppe Viale,

Suzette Delaloge,

JeanYves Pierga,

Étienne Brain,

Sylvain Causeret,

Mauro Delorenzi,

Annuska M. Glas,

Vassilis Golfinopoulos,

Theodora Goulioti,

Susan Knox,

Erika Matos,

Bart Meulemans,

Peter A. Neijenhuis,

Ulrike Nitz,

Rodolfo Passalacqua,

Peter M. Ravdin,

Isabel T. Rubio,

Mahasti Saghatchian,

Tineke J. Smilde,

Christos Sotiriou,

Lisette Stork,

Carolyn Straehle,

Geraldine Thomas,

Alastair M. Thompson,

Jacobus M. van der Hoeven,

Peter Vuylsteke,

René Bernards,

Konstantinos Tryfonidis,

Emiel J. Rutgers,

Martine Piccart

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1602253

Subject(s) - breast cancer , stage (stratigraphy) , oncology , medicine , gene signature , pathological , adjuvant chemotherapy , cancer , signature (topology) , adjuvant , chemotherapy , gene , biology , gene expression , paleontology , biochemistry , geometry , mathematics

The 70-gene signature test (MammaPrint) has been shown to improve prediction of clinical outcome in women with early-stage breast cancer. We sought to provide prospective evidence of the clinical utility of the addition of the 70-gene signature to standard clinical-pathological criteria in selecting patients for adjuvant chemotherapy.

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