Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women | Zendy

Annaléne Nel | Zendy; Neliëtte van Niekerk | Zendy; Saidi Kapiga | Zendy; LindaGail Bekker | Zendy; Cynthia Gama | Zendy; Katherine Gill | Zendy; Anatoli Kamali | Zendy; Philip Kotze | Zendy; Cheryl Louw | Zendy; Zonke Mabude | Zendy; Nokuthula Miti | Zendy; Sylvia Kusemererwa | Zendy; Hugo Tempelman | Zendy; Hannelie Carstens | Zendy; Bríd Devlin | Zendy; Michelle Isaacs | Zendy; Mariëtte Malherbe | Zendy; Winél Mans | Zendy; Jeremy Nuttall | Zendy; Marisa Russell | Zendy; Smangaliso Ntshele | Zendy; Marlie Smit | Zendy; Leonard Nichiren Solai | Zendy; Patrick Spence | Zendy; John Steytler | Zendy; Kathleen Marie Windle | Zendy; Maarten Borremans | Zendy; Sophie Resseler | Zendy; Jens Van Roey | Zendy; Wim Parys | Zendy; Tony Vangeneugden | Zendy; Ben Van Baelen | Zendy; Zeda Rosenberg | Zendy

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Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women

Author(s) -

Annaléne Nel,

Neliëtte van Niekerk,

Saidi Kapiga,

LindaGail Bekker,

Cynthia Gama,

Katherine Gill,

Anatoli Kamali,

Philip Kotze,

Cheryl Louw,

Zonke Mabude,

Nokuthula Miti,

Sylvia Kusemererwa,

Hugo Tempelman,

Hannelie Carstens,

Bríd Devlin,

Michelle Isaacs,

Mariëtte Malherbe,

Winél Mans,

Jeremy Nuttall,

Marisa Russell,

Smangaliso Ntshele,

Marlie Smit,

Leonard Nichiren Solai,

Patrick Spence,

John Steytler,

Kathleen Marie Windle,

Maarten Borremans,

Sophie Resseler,

Jens Van Roey,

Wim Parys,

Tony Vangeneugden,

Ben Van Baelen,

Zeda Rosenberg

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1602046

Subject(s) - medicine , seroconversion , hazard ratio , placebo , confidence interval , vaginal ring , incidence (geometry) , gynecology , obstetrics , human immunodeficiency virus (hiv) , population , family planning , immunology , physics , environmental health , optics , research methodology , alternative medicine , pathology

The incidence of human immunodeficiency virus (HIV) infection remains high among women in sub-Saharan Africa. We evaluated the safety and efficacy of extended use of a vaginal ring containing dapivirine for the prevention of HIV infection in 1959 healthy, sexually active women, 18 to 45 years of age, from seven communities in South Africa and Uganda.

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