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Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke
Author(s) -
Craig S. Anderson,
Thompson Robinson,
Richard I. Lindley,
Hisatomi Arima,
Pablo M. Lavados,
TsongHai Lee,
Joseph P. Broderick,
Xiaoying Chen,
Guofang Chen,
Vijay K. Sharma,
Jong S. Kim,
Trung Quoc Nguyen,
Yongjun Cao,
Mark Parsons,
Christopher Levi,
Yining Huang,
Verónica V. Olavarría,
Andrew M. Demchuk,
Philip M. Bath,
Geoffrey A. Donnan,
Sheila Cristina Ouriques Martins,
Octávio Marques PontesNeto,
Federico Silva,
Stefano Ricci,
Christine Roffe,
Jeyaraj Pandian,
Laurent Billot,
Mark Woodward,
Qiang Li,
Xia Wang,
JiGuang Wang,
John Chalmers
Publication year - 2016
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1515510
Subject(s) - medicine , intracerebral hemorrhage , modified rankin scale , confidence interval , stroke (engine) , odds ratio , randomization , anesthesia , randomized controlled trial , surgery , glasgow coma scale , ischemic stroke , ischemia , mechanical engineering , engineering
Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose of intravenous alteplase may improve recovery along with a reduced risk of intracerebral hemorrhage.

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