A Worldwide Map ofPlasmodium falciparumK13-Propeller Polymorphisms | Zendy

Didier Ménard | Zendy; Nimol Khim | Zendy; Johann Beghain | Zendy; Ayôla Akim Adégnika | Zendy; Mohammad Shafiul Alam | Zendy; Olukemi K. Amodu | Zendy; Ghulam Rahim-Awab | Zendy; Céline Barnadas | Zendy; Antoine Berry | Zendy; Yap Boum | Zendy; Maria Dorina Bustos | Zendy; Jun Cao | Zendy; Jun-Hu Chen | Zendy; Louis Collet | Zendy; Liwang Cui | Zendy; Garib-Das Thakur | Zendy; Alioune Dièye | Zendy; Djibrine Djallé | Zendy; Améyo M. Dorkenoo | Zendy; Carole E. Eboumbou-Moukoko | Zendy; Fe-Esperanza-Caridad J. Espino | Zendy; Thierry Fandeur | Zendy; Maria-Fatima Ferreira-da-Cruz | Zendy; Abebe A. Fola | Zendy; HansPeter Fuehrer | Zendy; Abdillahi Mohamed Hassan | Zendy; Sócrates Herrera | Zendy; Bouasy Hongvanthong | Zendy; Sandrine Houzé | Zendy; Maman Laminou Ibrahim | Zendy; Mohammad Jahirul-Karim | Zendy; Lubin Jiang | Zendy; Shigeyuki Kano | Zendy; Wasif Ali-Khan | Zendy; Maniphone Khanthavong | Zendy; Peter G. Kremsner | Zendy; Marcus Lacerda | Zendy; Rithea Leang | Zendy; Mindy Leelawong | Zendy; Li Mei | Zendy; Khin Lin | Zendy; Jean-Baptiste Mazarati | Zendy; Sandie Ménard | Zendy; Isabelle Morlais | Zendy; Hypolite Muhindo Mavoko | Zendy; L. Musset | Zendy; Kesara NaBangchang | Zendy; Michael Nambozi | Zendy; Karamoko Niaré | Zendy; Harald Noedl | Zendy; JeanBosco Ouédraogo | Zendy; Dylan R. Pillai | Zendy; Bruno Pradines | Zendy; Bui Quang-Phuc | Zendy; Michael Ramharter | Zendy; Milijaona Randrianarivelojosia | Zendy; Jetsumon Sattabongkot | Zendy; Abdiqani Sheikh-Omar | Zendy; Kigbafori D. Silué | Zendy; Sodiomon B. Sirima | Zendy; Colin J. Sutherland | Zendy; Din Syafruddin | Zendy; Rachida Tahar | Zendy; Lin-Hua Tang | Zendy; Offianan André Touré | Zendy; Patrick Tshibangu-wa-Tshibangu | Zendy; Inès Vigan-Womas | Zendy; Marian Warsame | Zendy; Lyndes Wini | Zendy; Sedigheh Zakeri | Zendy; Saorin Kim | Zendy; Rotha Eam | Zendy; Laura Berne | Zendy; Chanra Khean | Zendy; Sophy Chy | Zendy; Malen Ken | Zendy; Kaknika Loch | Zendy; Lydie Canier | Zendy; Valentine Duru | Zendy; Eric Legrand | Zendy; Jean-Christophe Barale | Zendy; Barbara H. Stokes | Zendy; Judith Straimer | Zendy; Benoît Witkowski | Zendy; David A. Fidock | Zendy; Christophe Rogier | Zendy; Pascal Ringwald | Zendy; Frédéric Ariey | Zendy; Odile MercereauPuijalon | Zendy

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A Worldwide Map ofPlasmodium falciparumK13-Propeller Polymorphisms

Author(s) -

Didier Ménard,

Nimol Khim,

Johann Beghain,

Ayôla Akim Adégnika,

Mohammad Shafiul Alam,

Olukemi K. Amodu,

Ghulam Rahim-Awab,

Céline Barnadas,

Antoine Berry,

Yap Boum,

Maria Dorina Bustos,

Jun Cao,

Jun-Hu Chen,

Louis Collet,

Liwang Cui,

Garib-Das Thakur,

Alioune Dièye,

Djibrine Djallé,

Améyo M. Dorkenoo,

Carole E. Eboumbou-Moukoko,

Fe-Esperanza-Caridad J. Espino,

Thierry Fandeur,

Maria-Fatima Ferreira-da-Cruz,

Abebe A. Fola,

HansPeter Fuehrer,

Abdillahi Mohamed Hassan,

Sócrates Herrera,

Bouasy Hongvanthong,

Sandrine Houzé,

Maman Laminou Ibrahim,

Mohammad Jahirul-Karim,

Lubin Jiang,

Shigeyuki Kano,

Wasif Ali-Khan,

Maniphone Khanthavong,

Peter G. Kremsner,

Marcus Lacerda,

Rithea Leang,

Mindy Leelawong,

Li Mei,

Khin Lin,

Jean-Baptiste Mazarati,

Sandie Ménard,

Isabelle Morlais,

Hypolite Muhindo Mavoko,

L. Musset,

Kesara NaBangchang,

Michael Nambozi,

Karamoko Niaré,

Harald Noedl,

JeanBosco Ouédraogo,

Dylan R. Pillai,

Bruno Pradines,

Bui Quang-Phuc,

Michael Ramharter,

Milijaona Randrianarivelojosia,

Jetsumon Sattabongkot,

Abdiqani Sheikh-Omar,

Kigbafori D. Silué,

Sodiomon B. Sirima,

Colin J. Sutherland,

Din Syafruddin,

Rachida Tahar,

Lin-Hua Tang,

Offianan André Touré,

Patrick Tshibangu-wa-Tshibangu,

Inès Vigan-Womas,

Marian Warsame,

Lyndes Wini,

Sedigheh Zakeri,

Saorin Kim,

Rotha Eam,

Laura Berne,

Chanra Khean,

Sophy Chy,

Malen Ken,

Kaknika Loch,

Lydie Canier,

Valentine Duru,

Eric Legrand,

Jean-Christophe Barale,

Barbara H. Stokes,

Judith Straimer,

Benoît Witkowski,

David A. Fidock,

Christophe Rogier,

Pascal Ringwald,

Frédéric Ariey,

Odile MercereauPuijalon

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1513137

Subject(s) - nonsynonymous substitution , plasmodium falciparum , artemisinin , biology , malaria , genetics , allele , dihydroartemisinin , mutation , gene , immunology , genome

Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)-propeller domains are the major determinant of resistance has provided opportunities for monitoring such resistance on a global scale.

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