Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone | Zendy

David A. Stempel | Zendy; Ibrahim Raphiou | Zendy; Kenneth M. Kral | Zendy; Anne Yeakey | Zendy; Amanda Emmett | Zendy; Charlene M. Prazma | Zendy; Kathleen S. Buaron | Zendy; Steven Pascoe | Zendy

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Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone

Author(s) -

David A. Stempel,

Ibrahim Raphiou,

Kenneth M. Kral,

Anne Yeakey,

Amanda Emmett,

Charlene M. Prazma,

Kathleen S. Buaron,

Steven Pascoe

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1511049

Subject(s) - salmeterol , fluticasone propionate , medicine , fluticasone , asthma , inhalation , anesthesia

The safe and appropriate use of long-acting beta-agonists (LABAs) for the treatment of asthma has been widely debated. In two large clinical trials, investigators found a potential risk of serious asthma-related events associated with LABAs. This study was designed to evaluate the risk of administering the LABA salmeterol in combination with an inhaled glucocorticoid, fluticasone propionate.

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