Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves
Author(s) -
Raj Makkar,
Gregory P. Fontana,
Hasan Jilaihawi,
Tarun Chakravarty,
Klaus F. Kofoed,
Ole De Backer,
Federico M. Asch,
Carlos E. Ruiz,
Niels Thue Olsen,
Alfredo Trento,
John D. Friedman,
Daniel S. Berman,
Wen Cheng,
Muhammad Kashif,
Vladimir Jelnin,
Chad Kliger,
Hongfei Guo,
Augusto D. Pichard,
Neil J. Weissman,
Samir Kapadia,
Eric Manasse,
Deepak L. Bhatt,
Martin B. Leon,
Lars Søndergaard
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1509233
Subject(s) - medicine , subclinical infection , leaflet (botany) , thrombosis , cardiology , stroke (engine) , aortic valve , valve replacement , computed tomography , surgery , radiology , stenosis , mechanical engineering , paleontology , engineering , biology
A finding of reduced aortic-valve leaflet motion was noted on computed tomography (CT) in a patient who had a stroke after transcatheter aortic-valve replacement (TAVR) during an ongoing clinical trial. This finding raised a concern about possible subclinical leaflet thrombosis and prompted further investigation.
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