Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children
Author(s) -
Michelle M. Stein,
Cara L. Hrusch,
Justyna Gozdz,
Catherine Igartua,
Vadim Pivniouk,
Sean Murray,
Julie G. Ledford,
Mauricius Marques dos Santos,
Rebecca L. Anderson,
Nervana Metwali,
Julia W. Neilson,
Raina M. Maier,
Jack A. Gilbert,
Mark Holbreich,
Peter S. Thorne,
Fernando D. Martínez,
Erika von Mutius,
Donata Vercelli,
Carole Ober,
Anne I. Sperling
Publication year - 2016
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1508749
Subject(s) - genetic genealogy , asthma , immunology , immune system , medicine , immunity , innate immune system , allergy , immune dysregulation , demography , environmental health , population , sociology
The Amish and Hutterites are U.S. agricultural populations whose lifestyles are remarkably similar in many respects but whose farming practices, in particular, are distinct; the former follow traditional farming practices whereas the latter use industrialized farming practices. The populations also show striking disparities in the prevalence of asthma, and little is known about the immune responses underlying these disparities.
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