Germline Mutations in Predisposition Genes in Pediatric Cancer | Zendy

Jinghui Zhang | Zendy; Michael F. Walsh | Zendy; Gang Wu | Zendy; Michael N. Edmonson | Zendy; Tanja A. Grüber | Zendy; John Easton | Zendy; Dale J. Hedges | Zendy; Xiaotu Ma | Zendy; Xin Zhou | Zendy; Donald Yergeau | Zendy; Mark R. Wilkinson | Zendy; Bhavin Vadodaria | Zendy; Xiang Chen | Zendy; Rose B. McGee | Zendy; Stacy J. HinesDowell | Zendy; Regiuccio | Zendy; Emily A. Quinn | Zendy; Sheila Shurtleff | Zendy; Michael Rusch | Zendy; Aman Patel | Zendy; Jared Becksfort | Zendy; Shuoguo Wang | Zendy; Meaghann S. Weaver | Zendy; Li Ding | Zendy; Elaine R. Mardis | Zendy; Richard K. Wilson | Zendy; Amar Gajjar | Zendy; David W. Ellison | Zendy; Alberto S. Pappo | Zendy; ChingHon Pui | Zendy; Kim E. Nichols | Zendy; James R. Downing | Zendy

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Germline Mutations in Predisposition Genes in Pediatric Cancer

Author(s) -

Jinghui Zhang,

Michael F. Walsh,

Gang Wu,

Michael N. Edmonson,

Tanja A. Grüber,

John Easton,

Dale J. Hedges,

Xiaotu Ma,

Xin Zhou,

Donald Yergeau,

Mark R. Wilkinson,

Bhavin Vadodaria,

Xiang Chen,

Rose B. McGee,

Stacy J. HinesDowell,

Regiuccio,

Emily A. Quinn,

Sheila Shurtleff,

Michael Rusch,

Aman Patel,

Jared Becksfort,

Shuoguo Wang,

Meaghann S. Weaver,

Li Ding,

Elaine R. Mardis,

Richard K. Wilson,

Amar Gajjar,

David W. Ellison,

Alberto S. Pappo,

ChingHon Pui,

Kim E. Nichols,

James R. Downing

Publication year - 2015

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1508054

Subject(s) - germline , genetics , germline mutation , gene , biology , mutation , computational biology

The prevalence and spectrum of predisposing mutations among children and adolescents with cancer are largely unknown. Knowledge of such mutations may improve the understanding of tumorigenesis, direct patient care, and enable genetic counseling of patients and families.

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