Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease | Zendy

Nicolaus Kröger | Zendy; Carlos Solano | Zendy; Christine Wolschke | Zendy; Giuseppe Bandini | Zendy; Francesca Patriarca | Zendy; Massimo Pini | Zendy; Ar Nagler | Zendy; Carmine Selleri | Zendy; Antonio M. Risitano | Zendy; Giuseppe Messina | Zendy; Wolfgang Bethge | Zendy; Jaime Pérez de Oteyza | Zendy; Rafael F. Duarte | Zendy; Angelo Michele Carella | Zendy; Michele Cimminiello | Zendy; Stefano Guidi | Zendy; Jürgen Finke | Zendy; Nicola Mordini | Zendy; Christelle Ferrà | Zendy; Jorge Sierra | Zendy; Domenico Russo | Zendy; Mario Petrini | Zendy; Giuseppe Milone | Zendy; Fabio Benedetti | Zendy; Marion Heinzelmann | Zendy; Domenico Pastore | Zendy; Manuel Jurado | Zendy; Elisabetta Terruzzi | Zendy; Franco Narni | Zendy; Andreas Völp | Zendy; Francis Ayuk | Zendy; Tapani Ruutu | Zendy; Francesca Bonifazi | Zendy

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Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease

Author(s) -

Nicolaus Kröger,

Carlos Solano,

Christine Wolschke,

Giuseppe Bandini,

Francesca Patriarca,

Massimo Pini,

Ar Nagler,

Carmine Selleri,

Antonio M. Risitano,

Giuseppe Messina,

Wolfgang Bethge,

Jaime Pérez de Oteyza,

Rafael F. Duarte,

Angelo Michele Carella,

Michele Cimminiello,

Stefano Guidi,

Jürgen Finke,

Nicola Mordini,

Christelle Ferrà,

Jorge Sierra,

Domenico Russo,

Mario Petrini,

Giuseppe Milone,

Fabio Benedetti,

Marion Heinzelmann,

Domenico Pastore,

Manuel Jurado,

Elisabetta Terruzzi,

Franco Narni,

Andreas Völp,

Francis Ayuk,

Tapani Ruutu,

Francesca Bonifazi

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1506002

Subject(s) - medicine , cumulative incidence , graft versus host disease , gastroenterology , hematopoietic stem cell transplantation , transplantation , confidence interval , regimen , incidence (geometry) , prospective cohort study , immunology , physics , optics

Chronic graft-versus-host disease (GVHD) is the leading cause of later illness and death after allogeneic hematopoietic stem-cell transplantation. We hypothesized that the inclusion of antihuman T-lymphocyte immune globulin (ATG) in a myeloablative conditioning regimen for patients with acute leukemia would result in a significant reduction in chronic GVHD 2 years after allogeneic peripheral-blood stem-cell transplantation from an HLA-identical sibling.

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