Open AccessClinical Significance of Symptoms in Smokers with Preserved Pulmonary Function
Author(s) -
Prescott G. Woodruff,
R. Graham Barr,
Eugene R. Bleecker,
Stephanie A. Christenson,
David Couper,
Jeffrey L. Curtis,
Natalia Gouskova,
Nadia N. Hansel,
Eric A. Hoffman,
Richard E. Kanner,
Eric C. Kleerup,
Stephen C. Lazarus,
Fernando J. Martínez,
Robert Paine,
Stephen I. Rennard,
Donald P. Tashkin,
MeiLan K. Han
Publication year - 2016
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1505971
Subject(s) - vital capacity , spirometry , medicine , copd , pulmonary function testing , bronchodilator , pulmonary disease , bronchodilator agents , clinical significance , cardiology , physical therapy , intensive care medicine , lung function , asthma , lung , diffusing capacity
Currently, the diagnosis of chronic obstructive pulmonary disease (COPD) requires a ratio of forced expiratory volume in 1 second (FEV1) to forced vital capacity (FVC) of less than 0.70 as assessed by spirometry after bronchodilator use. However, many smokers who do not meet this definition have respiratory symptoms.
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