Effect of PCI on Long-Term Survival in Patients with Stable Ischemic Heart Disease
Author(s) -
Steven P. Sedlis,
Pamela Hartigan,
Koon Teo,
David J. Maron,
John A. Spertus,
G.B. John Mancini,
William J. Kostuk,
Bernard R. Chaitman,
Daniel S. Berman,
Jeffrey D. Lorin,
Marcin Dada,
William S. Weintraub,
William E. Boden
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1505532
Subject(s) - medicine , conventional pci , percutaneous coronary intervention , national death index , proportional hazards model , angina , veterans affairs , survival analysis , population , survival rate , hazard ratio , medical record , clinical trial , surgery , myocardial infarction , confidence interval , environmental health
Percutaneous coronary intervention (PCI) relieves angina in patients with stable ischemic heart disease, but clinical trials have not shown that it improves survival. Between June 1999 and January 2004, we randomly assigned 2287 patients with stable ischemic heart disease to an initial management strategy of optimal medical therapy alone (medical-therapy group) or optimal medical therapy plus PCI (PCI group) and did not find a significant difference in the rate of survival during a median follow-up of 4.6 years. We now report the rate of survival among the patients who were followed for up to 15 years.
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