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Cyclosporine before PCI in Patients with Acute Myocardial Infarction
Author(s) -
Thien-Tri Cung,
Olivier Morel,
Guillaume Cayla,
Gilles Rioufol,
David GarcíaDorado,
Denis Angoulvant,
Eric BonnefoyCudraz,
Patrice Guérin,
Meyer Elbaz,
Nicolas Delarche,
Pierre Coste,
Gérald Vanzetto,
M Metge,
JeanFrançois Aupetit,
Bernard Jouve,
Pascal Motreff,
Christophe Tron,
Jean-Noël Labèque,
Philippe Gabríel Steg,
Yves Cottin,
Grégoire Rangé,
J. Clerc,
Marc J. Claeys,
Patrick Coussement,
Fabrice Prunier,
Frédéric Moulin,
Olivier Roth,
Loïc Belle,
Philippe Dúbois,
Paul Barragan,
Martine Gilard,
Christophe Piot,
Patrice Colin,
F. De Poli,
MarieClaude Morice,
Omar Ider,
JeanLuc DuboisRandé,
Thierry Unterseeh,
Hervé Breton,
T Béard,
Didier Blanchard,
Gilles Grollier,
V. Malquarti,
Patrick Staat,
Arnaud Sudre,
Eskil Elmér,
Magnus J. Hansson,
Cyrille Bergerot,
Inesse Boussaha,
Claire Jossan,
Geneviève Dérumeaux,
Nathan Mewton,
Michel Ovize
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1505489
Subject(s) - medicine , myocardial infarction , percutaneous coronary intervention , cardiology , conventional pci , angina , culprit , placebo , ventricular remodeling , heart failure , adverse effect , stroke (engine) , alternative medicine , pathology , engineering , mechanical engineering
Experimental and clinical evidence suggests that cyclosporine may attenuate reperfusion injury and reduce myocardial infarct size. We aimed to test whether cyclosporine would improve clinical outcomes and prevent adverse left ventricular remodeling.

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