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A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer
Author(s) -
Gerard A. Silvestri,
Anil Vachani,
Duncan Whitney,
Michael Elashoff,
Kate Smith,
J. Scott Ferguson,
E. Parsons,
Nandita Mitra,
Jerome S. Brody,
Marc E. Lenburg,
Avrum Spira
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1504601
Subject(s) - medicine , lung cancer , bronchoscopy , receiver operating characteristic , confidence interval , bronchus , lung , lung cancer screening , respiratory disease , radiology , gastroenterology , pathology
Bronchoscopy is frequently nondiagnostic in patients with pulmonary lesions suspected to be lung cancer. This often results in additional invasive testing, although many lesions are benign. We sought to validate a bronchial-airway gene-expression classifier that could improve the diagnostic performance of bronchoscopy.

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