Polymer-free Drug-Coated Coronary Stents in Patients at High Bleeding Risk
Author(s) -
Philip Urban,
Ian T. Meredith,
Alexandre Abizaid,
Stuart J. Pocock,
Didier Carrié,
Christoph Naber,
Janusz Lipiecki,
Gert Richardt,
Andrés Íñiguez,
Philippe Brunel,
Mariano ValdésChávarri,
Philippe Garot,
Suneel Talwar,
Jacques Berland,
Mohamed Abdellaoui,
Franz R. Eberli,
Keith G. Oldroyd,
Robaayah Zambahari,
John Gregson,
Samantha Greene,
HansPeter Stoll,
MarieClaude Morice
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1503943
Subject(s) - medicine , percutaneous coronary intervention , stent , conventional pci , hazard ratio , myocardial infarction , surgery , target lesion , drug eluting stent , confidence interval , clinical endpoint , bare metal stent , randomized controlled trial
Patients at high risk for bleeding who undergo percutaneous coronary intervention (PCI) often receive bare-metal stents followed by 1 month of dual antiplatelet therapy. We studied a polymer-free and carrier-free drug-coated stent that transfers umirolimus (also known as biolimus A9), a highly lipophilic sirolimus analogue, into the vessel wall over a period of 1 month.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom