Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation | Zendy

James D. Douketis | Zendy; Alex C. Spyropoulos | Zendy; Scott Kaatz | Zendy; Richard C. Becker | Zendy; Joseph A. Caprini | Zendy; Andrew Dunn | Zendy; David García | Zendy; Alan K. Jacobson | Zendy; Amir K. Jaffer | Zendy; David F. Kong | Zendy; Sam Schulman | Zendy; Alexander G.G. Turpie | Zendy; Vic Hasselblad | Zendy; Thomas L. Ortel | Zendy

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Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation

Author(s) -

James D. Douketis,

Alex C. Spyropoulos,

Scott Kaatz,

Richard C. Becker,

Joseph A. Caprini,

Andrew Dunn,

David García,

Alan K. Jacobson,

Amir K. Jaffer,

David F. Kong,

Sam Schulman,

Alexander G.G. Turpie,

Vic Hasselblad,

Thomas L. Ortel

Publication year - 2015

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1501035

Subject(s) - medicine , perioperative , bridging (networking) , warfarin , atrial fibrillation , anesthesia , low molecular weight heparin , placebo , surgery , randomized controlled trial , anticoagulant , heparin , cardiology , computer network , alternative medicine , pathology , computer science

It is uncertain whether bridging anticoagulation is necessary for patients with atrial fibrillation who need an interruption in warfarin treatment for an elective operation or other elective invasive procedure. We hypothesized that forgoing bridging anticoagulation would be noninferior to bridging with low-molecular-weight heparin for the prevention of perioperative arterial thromboembolism and would be superior to bridging with respect to major bleeding.

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