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Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke
Author(s) -
Jeffrey L. Saver,
Mayank Goyal,
Alain Bonafé,
HansChristoph Diener,
Elad I. Levy,
Vítor Mendes Pereira,
Gregory W. Albers,
Christophe Cognard,
David J. Cohen,
Werner Hacke,
Olav Jansen,
Tudor G. Jovin,
Heinrich P. Mattle,
Raul G. Nogueira,
Adnan H. Siddiqui,
Dileep R. Yavagal,
Blaise Baxter,
Thomas Devlin,
Demetrius K. Lopes,
Vivek K. Reddy,
Richard du Mesnil de Rochemont,
Oliver C. Singer,
Reza Jahan
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1415061
Subject(s) - medicine , stroke (engine) , stent , tissue plasminogen activator , acute stroke , cardiology , surgery , anesthesia , mechanical engineering , engineering
Among patients with acute ischemic stroke due to occlusions in the proximal anterior intracranial circulation, less than 40% regain functional independence when treated with intravenous tissue plasminogen activator (t-PA) alone. Thrombectomy with the use of a stent retriever, in addition to intravenous t-PA, increases reperfusion rates and may improve long-term functional outcome.

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