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Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke
Author(s) -
Mayank Goyal,
Andrew M. Demchuk,
Bijoy K. Me,
Muneer Eesa,
Jeremy Rempel,
John Thornton,
Daniel Roy,
Tudor Jovin,
Robert A. Willinsky,
Biggya L. Sapkota,
Dar Dowlatshahi,
Donald Frei,
Noreen Kamal,
Walter Montanera,
Alexandre Y. Poppe,
Karla J. Ryckborst,
Frank L. Silver,
Ashfaq Shuaib,
Donatella Tampieri,
David Williams,
Oh Young Bang,
Blaise Baxter,
Paul Burns,
Hana Choe,
Ji Hoe Heo,
Christine A Holmstedt,
Brian T. Jankowitz,
Michael Kelly,
Guillermo Linares,
Jennifer Mandzia,
Jai Shankar,
SungIl Sohn,
Richard H. Swartz,
Philip A. Barber,
Shelagh B. Coutts,
Eric E. Smith,
William Morrish,
Alain Weill,
Suresh Subramaniam,
Alim P. Mitha,
John Wong,
Mark Lowerison,
Tolulope T. Sajobi,
Michael D. Hill
Publication year - 2015
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1414905
Subject(s) - medicine , modified rankin scale , solitaire cryptographic algorithm , collateral circulation , randomized controlled trial , occlusion , stroke (engine) , odds ratio , surgery , ischemia , ischemic stroke , mechanical engineering , engineering
Among patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with acute ischemic stroke with a small infarct core, a proximal intracranial arterial occlusion, and moderate-to-good collateral circulation.

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