Patiromer in Patients with Kidney Disease and Hyperkalemia Receiving RAAS Inhibitors
Author(s) -
Matthew R. Weir,
George L. Bakris,
David A. Bushinsky,
Martha Mayo,
Dahlia Garza,
Yuri Stasiv,
Janet Wittes,
Heidi ChristSchmidt,
Lance Berman,
Bertram Pitt
Publication year - 2014
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1410853
Subject(s) - hyperkalemia , medicine , liter , kidney disease , clinical endpoint , confidence interval , aldosterone , placebo , potassium , urology , gastroenterology , randomized controlled trial , pathology , chemistry , alternative medicine , organic chemistry
Hyperkalemia increases the risk of death and limits the use of inhibitors of the renin-angiotensin-aldosterone system (RAAS) in high-risk patients. We assessed the safety and efficacy of patiromer, a nonabsorbed potassium binder, in a multicenter, prospective trial.
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