Follow-up of Blood-Pressure Lowering and Glucose Control in Type 2 Diabetes
Author(s) -
Sophia Zoungas,
John Chalmers,
Bruce Neal,
Laurent Billot,
Qiang Li,
Yoichiro Hirakawa,
Hisatomi Arima,
Helen Monaghan,
Rohina Joshi,
Stephen Colagiuri,
Mark E. Cooper,
Paul Glasziou,
Diederick E. Grobbee,
Pavel Hamet,
Stephen Harrap,
Simon Heller,
Lisheng Liu,
Giuseppe Mancia,
Michel Marre,
David R. Matthews,
Carl Erik Mogensen,
Vlado Perkovic,
Neil R Poulter,
Anthony Rodgers,
Bryan Williams,
Stephen MacMahon,
Anushka Patel,
Mark Woodward
Publication year - 2014
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1407963
Subject(s) - medicine , glycated hemoglobin , indapamide , blood pressure , type 2 diabetes , hazard ratio , diabetes mellitus , placebo , perindopril , randomized controlled trial , clinical endpoint , confidence interval , surgery , endocrinology , alternative medicine , pathology
In the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) factorial trial, the combination of perindopril and indapamide reduced mortality among patients with type 2 diabetes, but intensive glucose control, targeting a glycated hemoglobin level of less than 6.5%, did not. We now report results of the 6-year post-trial follow-up.
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