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Enzalutamide in Metastatic Prostate Cancer before Chemotherapy
Author(s) -
Tomasz M. Beer,
Andrew J. Armstrong,
Dana E. Rathkopf,
Yohann Loriot,
Cora N. Sternberg,
Celestia S. Higano,
Peter Iversen,
Suman Bhattacharya,
Joan Carles,
Simon Chowdhury,
Ian D. Davis,
Johann S. de Bono,
Christopher P. Evans,
Karim Fizazi,
Anthony M. Joshua,
ChoungSoo Kim,
Go Kimura,
Paul N. Mainwaring,
Harry H. Mansbach,
Kurt Miller,
Sarah B. Noonberg,
Frank Perabo,
De Phung,
Fred Saad,
Howard I. Scher,
MaryEllen Taplin,
Peter Venner,
Bertrand Tombal
Publication year - 2014
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1405095
Subject(s) - enzalutamide , prostate cancer , medicine , oncology , chemotherapy , cancer , androgen receptor
Enzalutamide is an oral androgen-receptor inhibitor that prolongs survival in men with metastatic castration-resistant prostate cancer in whom the disease has progressed after chemotherapy. New treatment options are needed for patients with metastatic prostate cancer who have not received chemotherapy, in whom the disease has progressed despite androgen-deprivation therapy.

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