Open AccessMepolizumab Treatment in Patients with Severe Eosinophilic Asthma
Author(s) -
Héctor Ortega,
Mark C. Liu,
Ian Pavord,
Guy Brusselle,
J. Mark FitzGerald,
Alfredo Chetta,
Marc Humbert,
Lynn E. Katz,
Oliver N. Keene,
Steven W. Yancey,
Pascal Chanez
Publication year - 2014
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1403290
Subject(s) - mepolizumab , medicine , placebo , asthma , confidence interval , randomized controlled trial , anesthesia , eosinophil , pathology , alternative medicine
Some patients with severe asthma have frequent exacerbations associated with persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled glucocorticoids with or without oral glucocorticoids.
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