Simvastatin in the Acute Respiratory Distress Syndrome | Zendy

Daniel F. McAuley | Zendy; John G. Laffey | Zendy; Cecilia M. O’Kane | Zendy; Gavin D. Perkins | Zendy; Brian Mullan | Zendy; T. J. Trinder | Zendy; Paul Johnston | Zendy; Philip Hopkins | Zendy; Andrew J. Johnston | Zendy; Clíona McDowell | Zendy; Christine McNally | Zendy

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Simvastatin in the Acute Respiratory Distress Syndrome

Author(s) -

Daniel F. McAuley,

John G. Laffey,

Cecilia M. O’Kane,

Gavin D. Perkins,

Brian Mullan,

T. J. Trinder,

Paul Johnston,

Philip Hopkins,

Andrew J. Johnston,

Clíona McDowell,

Christine McNally

Publication year - 2014

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1403285

Subject(s) - medicine , simvastatin , ards , placebo , adverse effect , incidence (geometry) , clinical trial , respiratory distress , anesthesia , lung , physics , alternative medicine , pathology , optics

Studies in animals and in vitro and phase 2 studies in humans suggest that statins may be beneficial in the treatment of the acute respiratory distress syndrome (ARDS). This study tested the hypothesis that treatment with simvastatin would improve clinical outcomes in patients with ARDS.

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