Sofosbuvir and Ribavirin in HCV Genotypes 2 and 3
Author(s) -
Stefan Zeuzem,
Geoffrey Dusheiko,
Riina Salupere,
Alessandra Mangia,
Robert Flisiak,
Robert H. Hyland,
Ari Illeperuma,
Evguenia S. Svarovskaia,
Diana M. Brainard,
William T. Symonds,
G. Mani Subramanian,
John G. McHutchison,
Ola Weiland,
Hendrik W. Reesink,
Péter Ferenci,
Christophe Hézode,
Rafael Esteban
Publication year - 2014
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1316145
Subject(s) - sofosbuvir , ribavirin , medicine , hepatitis c virus , genotype , gastroenterology , regimen , placebo , hepatitis c , cirrhosis , immunology , virus , pathology , biology , gene , biochemistry , alternative medicine
In clinical trials, treatment with a combination of the nucleotide polymerase inhibitor sofosbuvir and the antiviral drug ribavirin was associated with high response rates among patients with hepatitis C virus (HCV) genotype 2 infection, with lower response rates among patients with HCV genotype 3 infection.
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