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Effects of Hypothermia for Perinatal Asphyxia on Childhood Outcomes
Author(s) -
Denis Azzopardi,
Brenda Strohm,
Neil Marlow,
Peter Brocklehurst,
Aniko Deierl,
Oya Eddama,
Julia Goodwin,
Henry L. Halliday,
Edmund Juszczak,
Olga Kapellou,
Malcolm I. Levene,
Louise Linsell,
Omar Omar,
Marianne Thoresen,
Nora Tusor,
Andrew Whitelaw,
A. David Edwards
Publication year - 2014
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1315788
Subject(s) - medicine , hypothermia , asphyxia , cerebral palsy , encephalopathy , relative risk , confidence interval , perinatal asphyxia , anesthesia , gestational age , neurocognitive , pediatrics , randomized controlled trial , surgery , pregnancy , physical therapy , cognition , psychiatry , biology , genetics
In the Total Body Hypothermia for Neonatal Encephalopathy Trial (TOBY), newborns with asphyxial encephalopathy who received hypothermic therapy had improved neurologic outcomes at 18 months of age, but it is uncertain whether such therapy results in longer-term neurocognitive benefits.

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