Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia
Author(s) -
Richard R. Furman,
Jeff P. Sharman,
Steven Coutré,
Bruce D. Cheson,
John M. Pagel,
Peter Hillmen,
Jacqueline C. Barrientos,
Andrew D. Zelenetz,
Thomas J. Kipps,
Ian W. Flinn,
Paolo Ghia,
Herbert Eradat,
Thomas J. Ervin,
Nicole Lamanna,
Bertrand Coiffier,
Andrew R. Pettitt,
Shuo Ma,
Stephan Stilgenbauer,
Paula Cramer,
Maria Aiello,
Dave M. Johnson,
Langdon L. Miller,
Daniel Li,
Thomas M. Jahn,
Roger Dansey,
Michael Hallek,
Susan O’Brien
Publication year - 2014
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1315226
Subject(s) - medicine , idelalisib , chronic lymphocytic leukemia , rituximab , ibrutinib , oncology , cd20 , leukemia , population , lymphocytic infiltration , chemotherapy , immunology , lymphoma , environmental health
Patients with relapsed chronic lymphocytic leukemia (CLL) who have clinically significant coexisting medical conditions are less able to undergo standard chemotherapy. Effective therapies with acceptable side-effect profiles are needed for this patient population.
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