Risk of Pediatric Celiac Disease According to HLA Haplotype and Country | Zendy

Edwin Liu | Zendy; HyeSeung Lee | Zendy; Carin Andrén Aronsson | Zendy; William Hagopian | Zendy; Sibylle Koletzko | Zendy; Marian Rewers | Zendy; George S. Eisenbarth | Zendy; Polly J. Bingley | Zendy; Ezio Bonifacio | Zendy; Ville Simell | Zendy; Daniel Agardh | Zendy

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Risk of Pediatric Celiac Disease According to HLA Haplotype and Country

Author(s) -

Edwin Liu,

HyeSeung Lee,

Carin Andrén Aronsson,

William Hagopian,

Sibylle Koletzko,

Marian Rewers,

George S. Eisenbarth,

Polly J. Bingley,

Ezio Bonifacio,

Ville Simell,

Daniel Agardh

Publication year - 2014

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1313977

Subject(s) - tissue transglutaminase , haplotype , human leukocyte antigen , disease , medicine , immunology , antibody , genetics , antigen , biology , allele , gene , biochemistry , enzyme

The presence of HLA haplotype DR3-DQ2 or DR4-DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG).

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