Use of Vibrio cholerae Vaccine in an Outbreak in Guinea | Zendy

Francisco J. Luquero | Zendy; Lise Grout | Zendy; Iza Ciglenečki | Zendy; Kéïta Sakoba | Zendy; Bala Traore | Zendy; Melat Heile | Zendy; Alpha Amadou Diallo | Zendy; Christian Itama | Zendy; AnneLaure Page | Zendy; MarieLaure Quilici | Zendy; Martin Mengel | Zendy; José Marı́a Eiros Bouza | Zendy; Micaela Serafini | Zendy; Dominique Legros | Zendy; Rebecca F. Grais | Zendy

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Use of Vibrio cholerae Vaccine in an Outbreak in Guinea

Author(s) -

Francisco J. Luquero,

Lise Grout,

Iza Ciglenečki,

Kéïta Sakoba,

Bala Traore,

Melat Heile,

Alpha Amadou Diallo,

Christian Itama,

AnneLaure Page,

MarieLaure Quilici,

Martin Mengel,

José Marı́a Eiros Bouza,

Micaela Serafini,

Dominique Legros,

Rebecca F. Grais

Publication year - 2014

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1312680

Subject(s) - vibrio cholerae , cholera , medicine , cholera vaccine , outbreak , environmental health , virology , biology , genetics , bacteria

The use of vaccines to prevent and control cholera is currently under debate. Shanchol is one of the two oral cholera vaccines prequalified by the World Health Organization; however, its effectiveness under field conditions and the protection it confers in the first months after administration remain unknown. The main objective of this study was to estimate the short-term effectiveness of two doses of Shanchol used as a part of the integrated response to a cholera outbreak in Africa.

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