A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing
Author(s) -
Stephen E. Kimmel,
Benjamin French,
Scott E. Kasner,
Julie A. Johnson,
Jeffrey L. Anderson,
Brian F. Gage,
Yves Rosenberg,
Charles S. Eby,
Rosemary Madigan,
Robert D. McBane,
Sherif Z. AbdelRahman,
Scott M. Stevens,
Steven H. Yale,
Emile R. Mohler,
Margaret C. Fang,
Vinay Shah,
Richard B. Horenstein,
Nita A. Limdi,
James A.S. Muldowney,
Jaspal Gujral,
Patrice Delafontaine,
Robert J. Desnick,
Thomas L. Ortel,
Henny H. Billett,
Robert C. Pendleton,
Nancy L. Geller,
Jonathan L. Halperin,
Samuel Z. Goldhaber,
Michael D. Caldwell,
Robert M. Califf,
Jonas H. Ellenberg
Publication year - 2013
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1310669
Subject(s) - medicine , dosing , pharmacogenetics , warfarin , medline , intensive care medicine , pharmacology , genotype , atrial fibrillation , gene , biochemistry , chemistry , political science , law
The clinical utility of genotype-guided (pharmacogenetically based) dosing of warfarin has been tested only in small clinical trials or observational studies, with equivocal results.
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