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Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
Author(s) -
Benjamin M. Scirica,
Deepak L. Bhatt,
Eugene Braunwald,
Philippe Gabríel Steg,
Jaime A. Davidson,
Boaz Hirshberg,
Peter Öhman,
Robert Frederich,
Stephen D. Wiviott,
Elaine Hoffman,
Matthew A. Cavender,
Jacob A. Udell,
Nihar R. Desai,
Ofri Mosenzon,
Darren K. McGuire,
Kausik K. Ray,
Lawrence A. Leiter,
Itamar Raz
Publication year - 2013
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1307684
Subject(s) - saxagliptin , medicine , hazard ratio , myocardial infarction , heart failure , placebo , stroke (engine) , type 2 diabetes , unstable angina , clinical endpoint , diabetes mellitus , confidence interval , randomized controlled trial , sitagliptin , endocrinology , mechanical engineering , alternative medicine , pathology , engineering
The cardiovascular safety and efficacy of many current antihyperglycemic agents, including saxagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor, are unclear.

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