CPAP versus Oxygen in Obstructive Sleep Apnea | Zendy

Daniel J. Gottlieb | Zendy; Naresh M. Punjabi | Zendy; Reena Mehra | Zendy; Sanjay R. Patel | Zendy; Stuart F. Quan | Zendy; Denise C. Babineau | Zendy; Russell P. Tracy | Zendy; Michael Rueschman | Zendy; Roger S. Blumenthal | Zendy; Eldrin F. Lewis | Zendy; Deepak L. Bhatt | Zendy; Susan Redline | Zendy

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CPAP versus Oxygen in Obstructive Sleep Apnea

Author(s) -

Daniel J. Gottlieb,

Naresh M. Punjabi,

Reena Mehra,

Sanjay R. Patel,

Stuart F. Quan,

Denise C. Babineau,

Russell P. Tracy,

Michael Rueschman,

Roger S. Blumenthal,

Eldrin F. Lewis,

Deepak L. Bhatt,

Susan Redline

Publication year - 2014

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1306766

Subject(s) - medicine , obstructive sleep apnea , continuous positive airway pressure , hypoxemia , blood pressure , sleep apnea , randomization , randomized controlled trial , polysomnography , sleep study , apnea , anesthesia

Obstructive sleep apnea is associated with hypertension, inflammation, and increased cardiovascular risk. Continuous positive airway pressure (CPAP) reduces blood pressure, but adherence is often suboptimal, and the benefit beyond management of conventional risk factors is uncertain. Since intermittent hypoxemia may underlie cardiovascular sequelae of sleep apnea, we evaluated the effects of nocturnal supplemental oxygen and CPAP on markers of cardiovascular risk.

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