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Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease
Author(s) -
Dick de Zeeuw,
Tadao Akizawa,
Paul Audhya,
George L. Bakris,
Melanie Chin,
Heidi ChristSchmidt,
Angie Goldsberry,
Mark T. Houser,
Melissa Krauth,
Hiddo J.L. Heerspink,
John J.V. McMurray,
Colin J. Meyer,
HansHenrik Parving,
Giuseppe Remuzzi,
Robert D. Toto,
Nosratola D. Vaziri,
Christoph Wanner,
Janet Wittes,
Danielle Wrolstad,
Glenn M. Chertow
Publication year - 2013
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1306033
Subject(s) - medicine , kidney disease , type 2 diabetes , diabetes mellitus , renin–angiotensin system , risk factor , endocrinology , disease , stage (stratigraphy) , urology , pharmacology , paleontology , blood pressure , biology
Although inhibitors of the renin-angiotensin-aldosterone system can slow the progression of diabetic kidney disease, the residual risk is high. Whether nuclear 1 factor (erythroid-derived 2)-related factor 2 activators further reduce this risk is unknown.

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