Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa | Zendy

Suzanne T. Anderson | Zendy; Myrsini Kaforou | Zendy; Andrew Brent | Zendy; Victoria Wright | Zendy; Claire M. Banwell | Zendy; George Chagaluka | Zendy; Amelia C. Crampin | Zendy; Hazel M. Dockrell | Zendy; Neil French | Zendy; Melissa Shea Hamilton | Zendy; Martin L. Hibberd | Zendy; Florian Kern | Zendy; Paul R. Langford | Zendy; Ling Ling | Zendy; Rachel Mlotha | Zendy; Tom H. M. Ottenhoff | Zendy; Sandy Pienaar | Zendy; Vashini Pillay | Zendy; J. Anthony G. Scott | Zendy; Hemed Twahir | Zendy; Robert J. Wilkinson | Zendy; Lachlan Coin | Zendy; Robert S. Heyderman | Zendy; Michael Levin | Zendy; Brian Eley | Zendy

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Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa

Author(s) -

Suzanne T. Anderson,

Myrsini Kaforou,

Andrew Brent,

Victoria Wright,

Claire M. Banwell,

George Chagaluka,

Amelia C. Crampin,

Hazel M. Dockrell,

Neil French,

Melissa Shea Hamilton,

Martin L. Hibberd,

Florian Kern,

Paul R. Langford,

Ling Ling,

Rachel Mlotha,

Tom H. M. Ottenhoff,

Sandy Pienaar,

Vashini Pillay,

J. Anthony G. Scott,

Hemed Twahir,

Robert J. Wilkinson,

Lachlan Coin,

Robert S. Heyderman,

Michael Levin,

Brian Eley

Publication year - 2014

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1303657

Subject(s) - tuberculosis , medicine , human immunodeficiency virus (hiv) , host (biology) , immunology , virology , host factors , virus , pathology , biology , genetics

Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with the human immunodeficiency virus (HIV).

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