MUC5B Promoter Polymorphism and Interstitial Lung Abnormalities | Zendy

Gary M. Hunninghake | Zendy; Hiroto Hatabu | Zendy; Yuka Okajima | Zendy; Wei Gao | Zendy; Josée Dupuis | Zendy; Jeanne C. Latourelle | Zendy; Mizuki Nishino | Zendy; Tetsuro Araki | Zendy; Oscar E. Zazueta | Zendy; Sila Kurugol | Zendy; James C. Ross | Zendy; Raúl San Jośe Estépar | Zendy; Elissa Murphy | Zendy; Mark P. Steele | Zendy; James E. Loyd | Zendy; Marvin I. Schwarz | Zendy; Tasha E. Fingerlin | Zendy; Iván O. Rosas | Zendy; George R. Washko | Zendy; George O'connor | Zendy; David A. Schwartz | Zendy

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MUC5B Promoter Polymorphism and Interstitial Lung Abnormalities

Author(s) -

Gary M. Hunninghake,

Hiroto Hatabu,

Yuka Okajima,

Wei Gao,

Josée Dupuis,

Jeanne C. Latourelle,

Mizuki Nishino,

Tetsuro Araki,

Oscar E. Zazueta,

Sila Kurugol,

James C. Ross,

Raúl San Jośe Estépar,

Elissa Murphy,

Mark P. Steele,

James E. Loyd,

Marvin I. Schwarz,

Tasha E. Fingerlin,

Iván O. Rosas,

George R. Washko,

George O'connor,

David A. Schwartz

Publication year - 2013

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1216076

Subject(s) - medicine , interstitial lung disease , odds ratio , gastroenterology , idiopathic pulmonary fibrosis , lung , genotype , population , framingham heart study , pathology , disease , framingham risk score , genetics , gene , environmental health , biology

A common promoter polymorphism (rs35705950) in MUC5B, the gene encoding mucin 5B, is associated with idiopathic pulmonary fibrosis. It is not known whether this polymorphism is associated with interstitial lung disease in the general population.

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