Dolutegravir plus Abacavir–Lamivudine for the Treatment of HIV-1 Infection
Author(s) -
Sharon Walmsley,
Antonio Antela,
Nathan Clumeck,
Dan Duiculescu,
Andrea Eberhard,
Félix Gutiérrez,
Laurent Hocqueloux,
Franco Maggiolo,
Uriel Sandkovsky,
Catherine Granier,
Keith A. Pappa,
Brian Wynne,
Sherene Min,
Garrett Nichols
Publication year - 2013
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1215541
Subject(s) - dolutegravir , abacavir , medicine , lamivudine , virology , integrase inhibitor , regimen , human immunodeficiency virus (hiv) , antiretroviral therapy , virus , viral load , hepatitis b virus
Dolutegravir (S/GSK1349572), a once-daily, unboosted integrase inhibitor, was recently approved in the United States for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in combination with other antiretroviral agents. Dolutegravir, in combination with abacavir-lamivudine, may provide a simplified regimen.
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