A Randomized Trial of Prolonged Co-trimoxazole in HIV-Infected Children in Africa | Zendy

Mutsa BwakuraDangarembizi | Zendy; Lindsay Kendall | Zendy; Sabrina BakeeraKitaka | Zendy; Patricia Nahirya-Ntege | Zendy; Rosette Keishanyu | Zendy; Kusum Nathoo | Zendy; Moira J. Spyer | Zendy; Adeodata Kekitiinwa | Zendy; Joseph Lutaakome | Zendy; Tawanda Mhute | Zendy; Phillip Kasirye | Zendy; Paula Munderi | Zendy; Victor Musiime | Zendy; Diana M. Gibb | Zendy; A. Sarah Walker | Zendy; Andrew J. Prendergast | Zendy

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A Randomized Trial of Prolonged Co-trimoxazole in HIV-Infected Children in Africa

Author(s) -

Mutsa BwakuraDangarembizi,

Lindsay Kendall,

Sabrina BakeeraKitaka,

Patricia Nahirya-Ntege,

Rosette Keishanyu,

Kusum Nathoo,

Moira J. Spyer,

Adeodata Kekitiinwa,

Joseph Lutaakome,

Tawanda Mhute,

Phillip Kasirye,

Paula Munderi,

Victor Musiime,

Diana M. Gibb,

A. Sarah Walker,

Andrew J. Prendergast

Publication year - 2014

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1214901

Subject(s) - medicine , trimethoprim , sulfamethoxazole , human immunodeficiency virus (hiv) , pediatrics , antiretroviral therapy , randomized controlled trial , virology , viral load , antibiotics , microbiology and biotechnology , biology

Co-trimoxazole (fixed-dose trimethoprim-sulfamethoxazole) prophylaxis administered before antiretroviral therapy (ART) reduces morbidity in children infected with the human immunodeficiency virus (HIV). We investigated whether children and adolescents receiving long-term ART in sub-Saharan Africa could discontinue co-trimoxazole.

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