ERCC1 Isoform Expression and DNA Repair in Non–Small-Cell Lung Cancer | Zendy

Luc Friboulet | Zendy; Ken A. Olaussen | Zendy; JeanPierre Pig | Zendy; Frances A. Shepherd | Zendy; MingSound Tsao | Zendy; Stephen L. Graziano | Zendy; Robert A. Kratzke | Zendy; Jean-Yves Douillard | Zendy; Lesley Seymour | Zendy; Robert Pirker | Zendy; Martin Filipits | Zendy; Fabrice André | Zendy; Éric Solary | Zendy; Florence Ponsonnailles | Zendy; Angélique Robin | Zendy; Annabelle Stoclin | Zendy; Nicolas Dorvault | Zendy; Frédéric Commo | Zendy; Julien Adam | Zendy; Elsa Vanhecke | Zendy; Patrick Saulnier | Zendy; Jürgen Thomale | Zendy; Thierry Le Chevalier | Zendy; Ariane Dunant | Zendy; Vanessa Rousseau | Zendy; Gwénaël Le Teuff | Zendy; Élisabeth Brambilla | Zendy; JeanCharles Soria | Zendy

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ERCC1 Isoform Expression and DNA Repair in Non–Small-Cell Lung Cancer

Author(s) -

Luc Friboulet,

Ken A. Olaussen,

JeanPierre Pig,

Frances A. Shepherd,

MingSound Tsao,

Stephen L. Graziano,

Robert A. Kratzke,

Jean-Yves Douillard,

Lesley Seymour,

Robert Pirker,

Martin Filipits,

Fabrice André,

Éric Solary,

Florence Ponsonnailles,

Angélique Robin,

Annabelle Stoclin,

Nicolas Dorvault,

Frédéric Commo,

Julien Adam,

Elsa Vanhecke,

Patrick Saulnier,

Jürgen Thomale,

Thierry Le Chevalier,

Ariane Dunant,

Vanessa Rousseau,

Gwénaël Le Teuff,

Élisabeth Brambilla,

JeanCharles Soria

Publication year - 2013

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1214271

Subject(s) - ercc1 , medicine , cisplatin , lung cancer , dna repair , biomarker , oncology , chemotherapy , nucleotide excision repair , cancer research , dna , biology , genetics

The excision repair cross-complementation group 1 (ERCC1) protein is a potential prognostic biomarker of the efficacy of cisplatin-based chemotherapy in non-small-cell lung cancer (NSCLC). Although several ongoing trials are evaluating the level of expression of ERCC1, no consensus has been reached regarding a method for evaluation.

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