TREM2 Variants in Alzheimer's Disease | Zendy

Rita Guerreiro | Zendy; Aleksandra Wojtas | Zendy; José Brás | Zendy; Minerva M. Carrasquillo | Zendy; Ekaterina Rogaeva | Zendy; Elisa Majounie | Zendy; Carlos Cruchaga | Zendy; Celeste Sassi | Zendy; John Kauwe | Zendy; Steven G. Younkin | Zendy; LiliNaz Hazrati | Zendy; John Collinge | Zendy; Jennifer M. Pocock | Zendy; Tammaryn Lashley | Zendy; Julie Williams | Zendy; JeanCharles Lambert | Zendy; Philippe Amouyel | Zendy; Alison Goate | Zendy; Rosa Rademakers | Zendy; Kevin Morgan | Zendy; John Powell | Zendy; Peter St GeorgeHyslop | Zendy; Andrew Singleton | Zendy; John Hardy | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

TREM2 Variants in Alzheimer's Disease

Author(s) -

Rita Guerreiro,

Aleksandra Wojtas,

José Brás,

Minerva M. Carrasquillo,

Ekaterina Rogaeva,

Elisa Majounie,

Carlos Cruchaga,

Celeste Sassi,

John Kauwe,

Steven G. Younkin,

LiliNaz Hazrati,

John Collinge,

Jennifer M. Pocock,

Tammaryn Lashley,

Julie Williams,

JeanCharles Lambert,

Philippe Amouyel,

Alison Goate,

Rosa Rademakers,

Kevin Morgan,

John Powell,

Peter St GeorgeHyslop,

Andrew Singleton,

John Hardy

Publication year - 2012

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1211851

Subject(s) - trem2 , dementia , loss function , disease , genetics , biology , gain of function , mutation , myeloid , receptor , function (biology) , alzheimer's disease , medicine , myeloid cells , cancer research , gene , phenotype

Homozygous loss-of-function mutations in TREM2, encoding the triggering receptor expressed on myeloid cells 2 protein, have previously been associated with an autosomal recessive form of early-onset dementia.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research