Deep Dermatophytosis and Inherited CARD9 Deficiency | Zendy

Fanny Lanternier | Zendy; Saad Pathan | Zendy; Quentin B. Vincent | Zendy; Luyan Liu | Zendy; Sophie Cypowyj | Zendy; Carolina Prando | Zendy; Mélanie Migaud | Zendy; L. Taibi | Zendy; A Ammar-Khodja | Zendy; O. Boudghène Stambouli | Zendy; Boumediene Guellil | Zendy; Frédérique Jacobs | Zendy; JeanChristophe Goffard | Zendy; Kinda Schepers | Zendy; V. del Mármol | Zendy; L. Boussofara | Zendy; M. Denguezli | Zendy; M. Larif | Zendy; H. Bachelez | Zendy; Laurence Michel | Zendy; MariePaule Lefranc | Zendy; R. J. Hay | Zendy; Grégory Jouvion | Zendy; Fabrice Chrétien | Zendy; S. Fraitag | Zendy; MarieElisabeth Bougnoux | Zendy; Merad Boudia | Zendy; Laurent Abel | Zendy; Olivier Lortholary | Zendy; JeanLaurent Casanova | Zendy; Capucine Pïcard | Zendy; Bodo Grimbacher | Zendy; Anne Puel | Zendy

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Deep Dermatophytosis and Inherited CARD9 Deficiency

Author(s) -

Fanny Lanternier,

Saad Pathan,

Quentin B. Vincent,

Luyan Liu,

Sophie Cypowyj,

Carolina Prando,

Mélanie Migaud,

L. Taibi,

A Ammar-Khodja,

O. Boudghène Stambouli,

Boumediene Guellil,

Frédérique Jacobs,

JeanChristophe Goffard,

Kinda Schepers,

V. del Mármol,

L. Boussofara,

M. Denguezli,

M. Larif,

H. Bachelez,

Laurence Michel,

MariePaule Lefranc,

R. J. Hay,

Grégory Jouvion,

Fabrice Chrétien,

S. Fraitag,

MarieElisabeth Bougnoux,

Merad Boudia,

Laurent Abel,

Olivier Lortholary,

JeanLaurent Casanova,

Capucine Pïcard,

Bodo Grimbacher,

Anne Puel

Publication year - 2013

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1208487

Subject(s) - dermatophyte , medicine , immunodeficiency , dermatology , lymph , mendelian inheritance , pathology , immunology , gene , biology , genetics , immune system

Deep dermatophytosis is a severe and sometimes life-threatening fungal infection caused by dermatophytes. It is characterized by extensive dermal and subcutaneous tissue invasion and by frequent dissemination to the lymph nodes and, occasionally, the central nervous system. The condition is different from common superficial dermatophyte infection and has been reported in patients with no known immunodeficiency. Patients are mostly from North African, consanguineous, multiplex families, which strongly suggests a mendelian genetic cause.

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