A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants | Zendy

Selidji Todagbé Agnandji | Zendy; Bertrand Lell | Zendy; José Francisco Fernandes | Zendy; Béatrice Peggy Abossolo | Zendy; Barbara Gaelle Nfono Ondo Methogo | Zendy; Anita L. Kabwende | Zendy; Ayôla Akim Adégnika | Zendy; Benjamin Mordmüller | Zendy; Saadou Issifou | Zendy; Peter G. Kremsner | Zendy; Jahit Sacarlal | Zendy; Pedro Aíde | Zendy; Miguel Lanaspa | Zendy; John J Aponte | Zendy; Sónia Machevo | Zendy; Sozinho Acácio | Zendy; Helder Bulo | Zendy; Betuel Sigaúque | Zendy; Eusébio Macete | Zendy; Pedro L. Alonso | Zendy; Salim Abdulla | Zendy; Nahya Salim | Zendy; Rose Minja | Zendy; Maxmillian Mpina | Zendy; Saumu Ahmed | Zendy; Ali Mohammed Ali | Zendy; Ali Mtoro | Zendy; Ali Hamad | Zendy; Paul Mutani | Zendy; Marcel Tanner | Zendy; Halidou Tinto | Zendy; Umberto D’Alessandro | Zendy; Hermann Sorgho | Zendy; Innocent Valéa | Zendy; Biébo Bihoun | Zendy; Issa Guiraud | Zendy; Bérenger Y. L. Kaboré | Zendy; Olivier Sombié | Zendy; Robert Tinga Guiguemdé | Zendy; JeanBosco Ouédraogo | Zendy; Mary J. Hamel | Zendy; Simon Kariuki | Zendy; Martina Oneko | Zendy; Chris Odero | Zendy; Kephas Otieno | Zendy; Norbert Awino | Zendy; Meredith McMorrow | Zendy; Vincent MuturiKioi | Zendy; Kayla F. Laserson | Zendy; Laurence Slutsker | Zendy; Walter Otieno | Zendy; Lucas Otieno | Zendy; Nekoye Otsyula | Zendy; Stacey Gondi | Zendy; Allan Otieno | Zendy; Victorine Owira | Zendy; Esther Oguk | Zendy; George S. Odongo | Zendy; Jon Ben Woods | Zendy; Bernhards Ogutu | Zendy; Patricia Njuguna | Zendy; Roma Chilengi | Zendy; Pauline Akoo | Zendy; Christine Kerubo | Zendy; Charity Maingi | Zendy; Trudie Lang | Zendy; Ally Olotu | Zendy; Philip Bejon | Zendy; Kevin Marsh | Zendy; Gabriel Mwambingu | Zendy; Seth OwusuAgyei | Zendy; Kwaku Poku Asante | Zendy; Kingsley Osei-Kwakye | Zendy; Owusu Boahen | Zendy; David Dosoo | Zendy; Isaac Asante | Zendy; George Adjei | Zendy; Evans Kwara | Zendy; Daniel Chandramohan | Zendy; Brian Greenwood | Zendy; John Lusingu | Zendy; Samwel Gesase | Zendy; Anangisye Malabeja | Zendy; Omari Abdul Msemo | Zendy; Coline Mahende | Zendy; Edwin Liheluka | Zendy; Lincoln Malle | Zendy; Martha Lemnge | Zendy; Thor G. Theander | Zendy; Chris Drakeley | Zendy; Daniel Ansong | Zendy; Tsiri Agbenyega | Zendy; Samuel Adjei | Zendy; Harry Owusu Boateng | Zendy; Theresa Rettig | Zendy; John Bawa | Zendy; Justice Sylverken | Zendy; David Sambian | Zendy; Anima Sarfo | Zendy; Alex Agyekum | Zendy; Francis Martinson | Zendy; Irving Hoffman | Zendy; Tisungane Mvalo | Zendy; Portia Kamthunzi | Zendy; Rutendo Nkomo | Zendy; Tapiwa Tembo | Zendy; Gerald Tegha | Zendy; Mercy Tsidya | Zendy; Jane Kilembe | Zendy; Chimwemwe Chawinga | Zendy; W. Ripley Ballou | Zendy; Joe Cohen | Zendy; Yolanda Guerra | Zendy; Erik Jongert | Zendy; Didier Lapierre | Zendy; Amanda Leach | Zendy; Marc Lievens | Zendy; Opokua OforiAnyinam | Zendy; Aurélie Olivier | Zendy; Johan Vekemans | Zendy; Terrell Carter | Zendy; David C. Kaslow | Zendy; Didier Leboulleux | Zendy; Christian Loucq | Zendy; Afiya Radford | Zendy; Barbara Savarese | Zendy; David Schellenberg | Zendy; Marla Sillman | Zendy; Preeti Vansadia | Zendy

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A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

Author(s) -

Selidji Todagbé Agnandji,

Bertrand Lell,

José Francisco Fernandes,

Béatrice Peggy Abossolo,

Barbara Gaelle Nfono Ondo Methogo,

Anita L. Kabwende,

Ayôla Akim Adégnika,

Benjamin Mordmüller,

Saadou Issifou,

Peter G. Kremsner,

Jahit Sacarlal,

Pedro Aíde,

Miguel Lanaspa,

John J Aponte,

Sónia Machevo,

Sozinho Acácio,

Helder Bulo,

Betuel Sigaúque,

Eusébio Macete,

Pedro L. Alonso,

Salim Abdulla,

Nahya Salim,

Rose Minja,

Maxmillian Mpina,

Saumu Ahmed,

Ali Mohammed Ali,

Ali Mtoro,

Ali Hamad,

Paul Mutani,

Marcel Tanner,

Halidou Tinto,

Umberto D’Alessandro,

Hermann Sorgho,

Innocent Valéa,

Biébo Bihoun,

Issa Guiraud,

Bérenger Y. L. Kaboré,

Olivier Sombié,

Robert Tinga Guiguemdé,

JeanBosco Ouédraogo,

Mary J. Hamel,

Simon Kariuki,

Martina Oneko,

Chris Odero,

Kephas Otieno,

Norbert Awino,

Meredith McMorrow,

Vincent MuturiKioi,

Kayla F. Laserson,

Laurence Slutsker,

Walter Otieno,

Lucas Otieno,

Nekoye Otsyula,

Stacey Gondi,

Allan Otieno,

Victorine Owira,

Esther Oguk,

George S. Odongo,

Jon Ben Woods,

Bernhards Ogutu,

Patricia Njuguna,

Roma Chilengi,

Pauline Akoo,

Christine Kerubo,

Charity Maingi,

Trudie Lang,

Ally Olotu,

Philip Bejon,

Kevin Marsh,

Gabriel Mwambingu,

Seth OwusuAgyei,

Kwaku Poku Asante,

Kingsley Osei-Kwakye,

Owusu Boahen,

David Dosoo,

Isaac Asante,

George Adjei,

Evans Kwara,

Daniel Chandramohan,

Brian Greenwood,

John Lusingu,

Samwel Gesase,

Anangisye Malabeja,

Omari Abdul Msemo,

Coline Mahende,

Edwin Liheluka,

Lincoln Malle,

Martha Lemnge,

Thor G. Theander,

Chris Drakeley,

Daniel Ansong,

Tsiri Agbenyega,

Samuel Adjei,

Harry Owusu Boateng,

Theresa Rettig,

John Bawa,

Justice Sylverken,

David Sambian,

Anima Sarfo,

Alex Agyekum,

Francis Martinson,

Irving Hoffman,

Tisungane Mvalo,

Portia Kamthunzi,

Rutendo Nkomo,

Tapiwa Tembo,

Gerald Tegha,

Mercy Tsidya,

Jane Kilembe,

Chimwemwe Chawinga,

W. Ripley Ballou,

Joe Cohen,

Yolanda Guerra,

Erik Jongert,

Didier Lapierre,

Amanda Leach,

Marc Lievens,

Opokua OforiAnyinam,

Aurélie Olivier,

Johan Vekemans,

Terrell Carter,

David C. Kaslow,

Didier Leboulleux,

Christian Loucq,

Afiya Radford,

Barbara Savarese,

David Schellenberg,

Marla Sillman,

Preeti Vansadia

Publication year - 2012

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1208394

Subject(s) - malaria vaccine , malaria , medicine , pediatrics , clinical trial , severe malaria , plasmodium falciparum , immunology

The candidate malaria vaccine RTS,S/AS01 reduced episodes of both clinical and severe malaria in children 5 to 17 months of age by approximately 50% in an ongoing phase 3 trial. We studied infants 6 to 12 weeks of age recruited for the same trial.

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