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Effect of Cinacalcet on Cardiovascular Disease in Patients Undergoing Dialysis
Author(s) -
Evolve Trial Investigators,
Glenn M. Chertow,
GA Block,
Ricardo CorreaRotter,
Tilman B. Drüeke,
J. Floege,
Goodman Wg,
Herzog Ca,
Yumi Kubo,
London Gm,
Mahaffey Kw,
Mix Tc,
Moe Sm,
Trotman Ml,
Wheeler Dc,
Parfrey Ps
Publication year - 2012
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1205624
Subject(s) - cinacalcet , medicine , calcimimetic , secondary hyperparathyroidism , kidney disease , disease , dialysis , hyperparathyroidism , calcification , parathyroid hormone , calcium
Disorders of mineral metabolism, including secondary hyperparathyroidism, are thought to contribute to extraskeletal (including vascular) calcification among patients with chronic kidney disease. It has been hypothesized that treatment with the calcimimetic agent cinacalcet might reduce the risk of death or nonfatal cardiovascular events in such patients.

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