Fractional Flow Reserve–Guided PCI versus Medical Therapy in Stable Coronary Disease
Author(s) -
Bernard De Bruyne,
Nico H.J. Pijls,
Bindu Kalesan,
Emanuele Barbato,
Pim A.L. Tonino,
Zsolt Piróth,
Nikola Jagić,
Sven MöbiusWinkler,
Gilles Rioufol,
Nils Witt,
Petr Kala,
Philip MacCarthy,
Thomas Engström,
Keith G. Oldroyd,
Kreton Mavromatis,
Ganesh Manoharan,
Peter VerLee,
Ole Frøbert,
Nick Curzen,
Jane B. Johnson,
Peter Jüni,
William F. Fearon
Publication year - 2012
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1205361
Subject(s) - fractional flow reserve , medicine , conventional pci , percutaneous coronary intervention , medical therapy , coronary artery disease , cardiology , coronary angiography , myocardial infarction
The preferred initial treatment for patients with stable coronary artery disease is the best available medical therapy. We hypothesized that in patients with functionally significant stenoses, as determined by measurement of fractional flow reserve (FFR), percutaneous coronary intervention (PCI) plus the best available medical therapy would be superior to the best available medical therapy alone.
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