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Quality-of-Life Effects of Prostate-Specific Antigen Screening
Author(s) -
Eveline A.M. Heijnsdijk,
Elisabeth M. Wever,
Anssi Auvinen,
Jonas Hugosson,
Stefano Ciatto,
Vera Nelen,
Maciej Kwiatkowski,
Arnauld Villers,
Álvaro Páez,
Sue Moss,
Marco Zappa,
Teuvo L.J. Tammela,
Tuukka Mäkinen,
Sigrid Carlsson,
Ida J. Korfage,
MarieLouise EssinkBot,
Suzie J. Otto,
Gerrit Draisma,
Chris H. Bangma,
Monique J. Roobol,
Fritz H. Schröder,
Harry J. de Koning
Publication year - 2012
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1201637
Subject(s) - overdiagnosis , medicine , prostate cancer , prostate specific antigen , quality of life (healthcare) , prostate , prostate cancer screening , oncology , gynecology , randomized controlled trial , cancer , urology , nursing
After 11 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) reported a 29% reduction in prostate-cancer mortality among men who underwent screening for prostate-specific antigen (PSA) levels. However, the extent to which harms to quality of life resulting from overdiagnosis and treatment counterbalance this benefit is uncertain.

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