Rivaroxaban in Patients with a Recent Acute Coronary Syndrome
Author(s) -
Jessica L. Mega,
Eugene Braunwald,
Stephen D. Wiviott,
JeanPierre Bassand,
Deepak L. Bhatt,
Christoph Bode,
Paul Burton,
Marc Cohen,
Nancy CookBruns,
Keith A.A. Fox,
Shinya Goto,
Sabina A. Murphy,
Alexei N. Plotnikov,
David J. Schneider,
Xiang Sun,
Freek W.A. Verheugt,
C. Michael Gibson
Publication year - 2011
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1112277
Subject(s) - medicine , rivaroxaban , acute coronary syndrome , myocardial infarction , placebo , hazard ratio , stroke (engine) , cardiology , thrombosis , anesthesia , confidence interval , warfarin , atrial fibrillation , mechanical engineering , alternative medicine , pathology , engineering
Acute coronary syndromes arise from coronary atherosclerosis with superimposed thrombosis. Since factor Xa plays a central role in thrombosis, the inhibition of factor Xa with low-dose rivaroxaban might improve cardiovascular outcomes in patients with a recent acute coronary syndrome.
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