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Rivaroxaban for Thromboprophylaxis in Acutely Ill Medical Patients
Author(s) -
Alexander T Cohen,
Theodore E. Spiro,
Harry R. Büller,
Lloyd Haskell,
Dayi Hu,
Russell D. Hull,
Alexandre Mebazaa,
Geno J. Merli,
Sebastian Schellong,
Alex C. Spyropoulos,
Victor F. Tapson
Publication year - 2013
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1111096
Subject(s) - medicine , rivaroxaban , placebo , clinical trial , anesthesia , emergency medicine , surgery , warfarin , atrial fibrillation , alternative medicine , pathology
The clinically appropriate duration of thromboprophylaxis in hospitalized patients with acute medical illnesses is unknown. In this multicenter, randomized, double-blind trial, we evaluated the efficacy and safety of oral rivaroxaban administered for an extended period, as compared with subcutaneous enoxaparin administered for a standard period, followed by placebo.

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