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Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes
Author(s) -
Peter Stalmans,
Matthew S. Benz,
Arnd Gandorfer,
Anselm Kampik,
Aniz Girach,
Stephen Pakola,
Julia A. Haller
Publication year - 2012
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1110823
Subject(s) - medicine , posterior vitreous detachment , vitrectomy , macular hole , ophthalmology , visual acuity , placebo , epiretinal membrane , surgery , pathology , alternative medicine
Vitreomacular adhesion can lead to pathologic traction and macular hole. The standard treatment for severe, symptomatic vitreomacular adhesion is vitrectomy. Ocriplasmin is a recombinant protease with activity against fibronectin and laminin, components of the vitreoretinal interface.

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