Potassium Channel KIR4.1 as an Immune Target in Multiple Sclerosis
Author(s) -
Ruchi Srivastava,
Muhammad Aslam,
Sudhakar Reddy Kalluri,
Lucas Schirmer,
Dorothea Buck,
Björn Tackenberg,
Veit Rothhammer,
Andrew Chan,
Ralf Gold,
Achim Berthele,
Jeffrey L. Bennett,
Thomas Korn,
Bernhard Hemmer
Publication year - 2012
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1110740
Subject(s) - multiple sclerosis , medicine , immune system , pathogenesis , immunology , demyelinating disease , central nervous system , autoimmune disease , experimental autoimmune encephalomyelitis , disease , neuroscience , pathology , antibody , biology
Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. Many findings suggest that the disease has an autoimmune pathogenesis; the target of the immune response is not yet known.
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