Germline Mutations inHOXB13and Prostate-Cancer Risk | Zendy

Charles M. Ewing | Zendy; Anna M. Ray | Zendy; Ethan M. Lange | Zendy; Kimberly A. Zuhlke | Zendy; Christiane M. Robbins | Zendy; Waibhav Tembe | Zendy; Kathleen E. Wiley | Zendy; Sarah D. Isaacs | Zendy; Dorhyun Johng | Zendy; Yunfei Wang | Zendy; Chris Bizon | Zendy; Guifang Yan | Zendy; Marta Gielzak | Zendy; Alan W. Partin | Zendy; Vijayalakshmi Shanmugam | Zendy; Tyler Izatt | Zendy; Shripad Sinari | Zendy; David W. Craig | Zendy; S. Lilly Zheng | Zendy; Patrick C. Walsh | Zendy; James E. Montie | Zendy; Jianfeng Xu | Zendy; John D. Carpten | Zendy; William B. Isaacs | Zendy; Kathleen A. Cooney | Zendy

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Germline Mutations inHOXB13and Prostate-Cancer Risk

Author(s) -

Charles M. Ewing,

Anna M. Ray,

Ethan M. Lange,

Kimberly A. Zuhlke,

Christiane M. Robbins,

Waibhav Tembe,

Kathleen E. Wiley,

Sarah D. Isaacs,

Dorhyun Johng,

Yunfei Wang,

Chris Bizon,

Guifang Yan,

Marta Gielzak,

Alan W. Partin,

Vijayalakshmi Shanmugam,

Tyler Izatt,

Shripad Sinari,

David W. Craig,

S. Lilly Zheng,

Patrick C. Walsh,

James E. Montie,

Jianfeng Xu,

John D. Carpten,

William B. Isaacs,

Kathleen A. Cooney

Publication year - 2012

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1110000

Subject(s) - prostate cancer , medicine , germline mutation , prostate , proband , cancer , oncology , germline , family history , mutation , genetics , risk factor , biology , gene

Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is poorly understood. Linkage studies have implicated chromosome 17q21-22 as a possible location of a prostate-cancer susceptibility gene.

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